Snake meat contains protein like any other type of meat. Protein is necessary for many body systems, including the development of muscles. Protein provides amino acids the body cannot obtain any other way, which do everything from building cell walls, to regulating hormones. Snake meat contains roughly 93 calories per 100g (3.5 oz) of raw meat, depending on the type of snake. This is roughly half the calories and one third the amount of fat of a similar amount of sirloin beef steak. Fewer calories and less fat content for the same weight of meat can aid dieters in controlling their weight.

As snake meat is not often sold commercially in the United States, it does not have particular, rigid health standards that other meats do. Rattlesnake meat is often sold from "Rattlesnake Roundups," which are similar in atmosphere to rodeos and have been accused of low standards of food preparation. This is of particular concern as rattlesnake meat in South America has been linked several times with severe strains of salmonella, which grows in the snake's gut. This bacteria is neutralized by proper handling and by cooking. Snakes, like other animals, may also contain parasites and other infections that can be transmitted to humans, which can also be neutralized by proper handling, freezing, and thorough cooking. Snake venom must enter the blood stream to pose any danger to people, so there are no concerns about poisoning from eating most snakes.
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Snake meat is relatively low in fat and calories, high in protein and some consider it a rising star in the food industry. However, like any type of meat, it should be prepared and cooked carefully to ensure it does not result in infection or food poisoning.